Bromination of Acetanilide

BROMINATION OF ACETANILIDE OBJECTIVE Aim of the experiment was too brominate acetaldehyde to form p-bromoacetanilide. INTRODUCTION Acetanilide is a chemical compound with the chemical formula of C6H5NH(COCH3). It is a crystalline solid that is prepared by acetylation of analine and is widely used in the dye industry. This crystalline solid is an odourless solid chemical that has a flake or leaf like appearance. It is also known as N phenylacetamide, acetanil or acetanilide. Its former trade name was antifebrin. As mentioned earlier acetanilide can be produced by reacting acetic anhydride with aniline.C6H5NH2 + (CH3CO)2O > C6H5NHCOCH3 + CH3COOH (http://www. mendelset. com/articles/680/preparation-recrystallization-acetanilide) (regensburg. de/Fakultaeten/nat_Fak_IV/Organische_Chemie/Didaktik/Keusch/Grafik/box_brom_ar1. gif) The second figure illustrates the process used in the laboratory to form bromoacetanilide. Recrystallization is of key importance in the experiment because this method is used to obtain the crystals. Recrystallization is a purification technique that removes impurities from a sample. An impure solid is placed in a liquid for example water or ethanol. It is then heated making the solid dissolve into the solvent.When the solvent cools back down again, the solid will precipitate out of the solution and leave the impurities behind, still dissolved in the solvent. This method purifies the solid. Acetanilide has many uses in both pharmaceutical and manufacturing industry. It is used as a precursor in the synthesis of penicillin and other pharmaceuticals. Originally it was the first aniline discovered to posses’ analgesic and antipyretic properties. A. Cahn and P. Hepp introduced it in the medical field in 1886. It was later to be discontinued in the medical field because of its toxic nature that was believed to cause cyanosis in the patient.Through further research it was also discovered that acetanilide is metabolized in the body to form paracetamol which was responsible for the analgesic and antipyretic property. Acetanilide is also used as an inhibitor in hydrogen pe roxide and is used to stabilize cellulose ester varnishes. It is also used in intermediation in rubber accelerator synthesis, dyes and dye intermediate synthesis and camphor synthesis. It is also used in the manufacture of sulfa drugs as it used for the production of 4-acetamidobenzenesulfonyl chloride, which is a key intermediate during this manufacture. METHOD 4. g of acetanilide was placed in a 100cm3 conical flask. It was then dissolved by adding 20 cm3 of glacial acetic acid, which was measured out in a measuring cylinder. 7. 0 cm3 was dispensed directly into the conical flask by use of a burette in one portion. The flask was then swirled to mix the contents. It was then covered with a clock glass and left in the fume hood for precisely 30 minutes long and swirled occasionally during the duration. Aqueous sodium hydrogen sulphite solution was added into the beaker until the red colour of the reactant disappeared this was to ensure that excess bromine formed during the reaction was destroyed. Feature Article –Â  Free-Radical BrominationThe lumps of solid found in the bottom of the flask were broken up to ensure no trapped bromine remained. As a precaution the first part of the experiment, which is outlined above, was carried out in a fumed cupboard. The flask was then taken out of the cupboard and the solid was then filtered by suction filtration using a Buchner funnel and washed with distilled water (2x 25cm3 portions). As much water as possible was removed from the solid by suction filtration then transferred to a 100cm3 conical flask.The crude solid was recrystallized by use of a minimum volume of a mixture of ethanol and water in the ratio 2: 1 at its boiling point. This mixture was added in portions using a steam bath as a heat source. The clear solution was then set aside to cool to near room temperature. The flask was cooled thoroughly in an ice/water bath afterwards the crystals were collected by suction filtration using a Hirsch funnel. The crystals were then washed with approximately 1cm3 of ice-cold ethanol/water mixture, dried by suction filtration and the mass and melting point range recorded.RESULTS Mass of empty weighing boat | 2. 25g| Mass of empty weighing boat+crystals| 5. 09g| Mass of crystals| 2. 8g| Melting range| 162 – 170C | DISCUSSION Bromine is generally a toxic, corrosive and a severe irritant to lung and eye tissues. Necessary precautions were taken during the experiment. One of the precautions taken was handling of the bromine solution in the reaction was done in a fumed cupboard. The excess bromine that was in the reaction was completely destroyed by adding aqueous sodium hydrogen sulphite solution.Protective gloves were worn to prevent the bromine liquid, ethanoic acid and sodium hydrogen sulphite from irritating the skin, as they are all skin irritants. The reaction that was carried out in the first part of the experiment is an electrophilic aromatic substitution. In the electrophilic aromatic substituti on, an electrophile reacts with the benzene ring this result in an electrophile replacing hydrogen in one of the phenyl carbons such that the product of the reaction has the electrophile bonded to one of the phenyl carbon.We did not use aniline in this practical as it has carcinogenic properties instead we used acetic anyhidride which is a milder version. The other products formed in this reaction hydrogen bromide and can be collected by hydrolizing(removing the hydrogen) to obtain the bromine. The percentage yield of the rection was calculated as follows Maas of products was 2. 84g Molar mass of bromo acetanilide=214 0. 284/ 214 = 0. 00133 4. 5g of acetanilide used Molar mass = 135 0. 45/134 = 0. 003 Yield 0. 00133/0. 003x 100 = 44. 3% yield.As clearly illustrated the percentage yield is less than a 100% this could be due to a number of reasons like some of the solid might have been lost during the suction or while washing the crystals with the water and ethanol mixture the weighin g scales could also have been inaccurate. CONCLUSION Better practical methods are required during the experiment to ensure a 100% yield. REFERENCES http://www. mendelset. com/articles/680/preparation-recrystallization-acetanilide regensburg. de/Fakultaeten/nat_Fak_IV/Organische_Chemie/Didaktik/Keusch/Grafik/box_brom_ar1. gif)

American expressionism: art and social change Essay

Art is a dynamic concept that has continued to evolve. Since its inception, art has evolved through various movements representing diverse themes and philosophies. Artists aligned to specific art movements have contributed in advancing their philosophies in the specific periods represented. From the 18th to the 21st century, art movements have impacted greatly on the society. The Romanticism Movement               Ã‚  The Romanticism movement originated towards the end of the 18th century in Europe. The movement advocated for the bold use of color to bring out the authentic emotional feel of an aesthetic experience. According to Dempsey (2002), the validation of intense emotional experience in visual arts stressed on emotions likes anxiety and horror. The liberal expression of an artist was an imperative aspect in the Romantic era; an artist’s feelings and expressions formed the basis of inspiration towards the production of art work (Scaglia, 2011). Creativity formed the basis of innovation upon which the Romanticism movement thrived. Nationalism and nature were central themes advanced by Romantic artists (Scaglia, 2011). The Romanticism movement placed an immense interest in nature. The reason behind the love for nature in artistic work during the movement was the philosophical tenet that a connection with nature was emotionally and ethically healthy. Moreover, artists based their works on a nationalism platform by fostering national development. The graphic design of the period drew strong influence from the political circles. The aristocratic political and social norms of the period triggered the rise of Romanticism. Romantic artists revolted against aristocracy sought to instill liberal tendencies through their expressions. On an economic ground, the industrial revolution had an influence on the movement. The movement was opposed to the corrupt nature that the society was adopting. The culture of liberalism and free expression contributed in the development of the movement. Thomas Jones’, The Bard (1774) Egide Charles (1834) The Belgian Revolution The visual arts explore the connection between Romanticism and nationalism. The paintings illustrate the artists’ use of nature as well as showing society’s need for nationalism respectively. Synchromism               Ã‚  The movement started in 1912 under the innovative works of Stanton Mc-Donald-Wright and Morgan Russell (Scaglia, 2011). The artists are acknowledged as among the pioneer abstract painters in the US. Wright and Russell used the â€Å"syncromy† style in their abstract paintings. The style was based on the artistic innovation, that sound and color have a connection. The idea behind Synchromism posited that colors in art can have the similar harmonious character as notes in music. The innovation behind the movement was that a painting can have the same complexity as music, if colors are arranged in scales. Contrary to other forms, Synchromism did not use lines, but only color and shape in artistic expressions. Having begun before the First World War, the movement posited that realism was no longer significant in visual art; there was need for a meaningful expression of art in the modern world (Scaglia, 2011). The culture of realism in the modern art world was fading; hence, the rise of the movement was attributed to the philosophy that innovation, and an artist’s feelings, as opposed to realism, was more dominant. Stanton MacDonald-Wright, Airplane Synchromy in Yellow-Orange (1920) Morgan Russell, Cosmic Synchromy (1913-14) The paintings by Wright and Russell display the use of color to come up with abstract paintings. The shapes illustrate the influence of imaginative artistic expression to come up ideas that are not in the realist physical nature. The style of the movement affects the graphic design of today by emphasizing on the use of color, particularly in the amount of hue used in painting. The intensity of color in contemporary art is an important factor to consider. Classical Realism               Ã‚  The movement became prominent towards the end of the 20th century. Designers in the movement regarded skill and beauty as imperative factors in their paintings (Scaglia, 2011). The movement’s style is edged on the visible world; this brings out its realism nature. Through an artist’s observation, he is in a position to bring out beauty and completeness (Scaglia, 2011). In Classical Realism, an artist concentrates on drawing and painting, and avoids mechanical aids. Classical Realism artists employ the artistic eye to explore harmony and skill in their paintings. A major cultural tenet behind the growth of Classical Realism is the belief that most artistic movements of the 20th century disregard the contribution of traditional art; hence, leading to the degradation of skill (Scaglia, 2011). Therefore, artists in this movement seek to restore the traditional concept of drawing and painting objects seen in the modern world. Jean-Là ©on Gà ©rà ´me. The artistic works illustrate the traditional art of drawing and painting objects from what people see. The emphasis on order, skill and harmony on the visual arts is a reflection of the realistic culture in artistic expressions. The movement influences modern graphic designs in using color to achieve harmony, and the utilization of skill. Expressionism               Ã‚  The movement started in Germany at the turn of the 20th century; Franz Marc and Alvar Cawà ©n were among the pioneer designers of the movement (Dijkstra, 2003). Stylistically, the movement sought to illustrate the world in a subjective perspective. In essence, artists in this movement sought to create meaning from their paintings, which was distant from the physical reality (Dijkstra, 2003). Artists achieve this through distorting the physical reality and evoking subjective emotional experience and mood. The growth of the movement in the early 20th century is attributed to the dehumanizing influence of industrialization. Moreover, expressionists were not in favor of realism; hence, sought to introduce an artistic style that would capitalize solely on the expressions of an artist. Alvar Cawà ©n, (Blind Musician), 1922 Franz Marc, Fighting Forms (1914) The paintings show an emphasis on the expression of emotion and mood. The paintings evoke a subjective meaning from what is intended in the physical world. The contemporary graphic industry draws inspiration from the movement through the use of color, foreground and background features to drive meaning. The Pop art movement               Ã‚  The Pop art movement begun in the 1950s in Britain and the United States; it was a break from the conventional orientations of art. Andy Warhol and Jasper Johns were among the prominent artists of the movement (Spilsbury, 2009). Argued as a reflection of modern art, the pop art movement introduced the use of imagery. The imagery used in the pop art movement derived its inspiration from the popular culture. Consequently, as a reflection of popular culture, pop art expressions are understood from the perspective of the approaches that produce them. The mass culture in the 1950s influenced the growth of the artistic movement; pop artists employed the images of the dominant culture in their graphic designs (Spilsbury, 2009).Technology also played an important role in the growth of the movement particularly in the expansion of abstract expressionism (Spilsbury, 2009). Andy Warhol, Campbell’s Soup I (1968) Jasper Johns, Flag 1954–1955 The artistic works by the above artists shows the reflection of the impact of popular culture in artistic expressions. Andy Warhol shows the influence of pop art in the advertising industry, while Jasper Johns expresses liberty as a popular culture through the representation of the flag. The movement influences contemporary graphic design by expanding the use of advertisement as an important platform of communication. Constructivism               Ã‚  The art movement, which started in 1919, popularized the use of art for social purposes. Experts assert that the movement sought to eliminate autonomy in art (Jones, 2006). Consequently, the growth of the movement is attributed to its participation in the Russian revolution. Constructivists came up with street designs that had social connotations during the revolution. During the early years of the movement, artists used their paintings as a means of communication to the people during the Russian civil war (Jones, 2006). The philosophy behind the movement was the advancement of social reconstruction. Constructivists used bright colors, arithmetic shapes and conspicuious lettering in their paintings in order to evoke emotions from the viewers and trigger deep understanding of the intended message. Vladimir Mayakovsky, An advertising construction (1921) Tatlin’s Tower (1919) The paintings above show the social connotations explored by constructivists. The use of bold colors and geometric shapes shows the intensity of communication developed by the artists. The constructivism movement affects modern graphic design by emphasizing on the use of art for social construction. Sensitizing people for political action through is an example of constructivist’s influence on contemporary art. Conclusion               Ã‚  Certainly, art is a dynamic phenomenon that represents the social, cultural and political expressions of different societies. The use of artistic features to demonstrate the influence of graphic design on a society shows that art is a powerful instrument; its ability to trigger emotional and objective connotations demonstrates its communication authority. References Dempsey, A. (2002). Art in the modern era: a guide to styles, schools & movements 1860 to the present. New York: Harry N. Abrams. Dijkstra, B. (2003). American expressionism: art and social change, 1920-1950. New York: H.N. Abrams, in association with the Columbus Museum of Art. Jones, A. (2006). A companion to contemporary art since 1945. Malden, MA: Blackwell Pub..Scaglia, B. (2011). The aesthetic variable: defining the contemporary art movement of the 2000s (classical realism, relational art, street art, stuckism, superflat, and more). United States: Webster’s Digital Services? :. Spilsbury, R. (2009). Pop art. Chicago, IL: Heinemann Library. Source document

Engage in personal development in health Essay

Outcome 1 1. Within my role as a support worker it is my duty to support an individual to complete everyday tasks. This can be activities such as food shopping, house chores, preparing food and drinks, making and attending appointments, attending college or day centre facilities, or participating in clubs for people with special needs. I have a responsibility to ensure the activity is achievable for the client and that I am providing the right support to achieve this. 2. As a support worker I have a duty to adhere to the codes of practice set out by my employers and also to ensure I adhere to the regulations set out by law. National Occupational Standards (NOS) ensure I give the appropriate support and care to an individual. Outcome 2 1. Reflective practice means thinking about and evaluating what I do and discussing any changes which could be made. Thinking about how I could have done something differently, what I did well and what I could have done better. It also means reflecting our own values, beliefs and experiences which shape our thoughts and ideas. By continuously evaluating my performance I am able to ensure I am providing the expected level of service set out within the company’s guidelines. 3. Everyone has different values, beliefs and experiences. We are more likely to be friendly and welcoming to people that share the same values and beliefs as us and less friendly to those that do not. However within my role it is expected that I provide the same level of care to every individual. Identifying your own beliefs and values will enable you to be aware of your reactions to others and enable them not to impact on the way you work. This is an important part of personal and professional development. Outcome 3 1. Codes of practice are put in place to enable you to understand your role and your responsibilities. Care plans are in place for each individual and the support I am required to provide is person-centred. I have a duty to ensure I am aware of each individual’s needs and to highlight any area I believe needs refocusing. Training should be relevant to the needs of individuals and provided by the company to ensure I adhere to regulations set out by law and the policies and procedures in place adhere to the current NOS guidelines. Outcome 4 1. Planning and reviewing my development usually takes place during planned supervision with my manager and my yearly appraisal. However I can approach either of my team leaders if I believe I require further training that is relevant to my role, they will speak with management on my behalf. Outside sources of support such as care managers, learning disabilities team or CQC may also highlight areas they feel further training is required if it is relevant to an individual I am to provide support too. Outcome 5 1. Attending training courses has enabled me to provide a level of care that is specific to the needs of the individual I am providing support too. During team meetings we may discuss serivce users and their needs. If a colleague has found something that works for them they will highlight it and it may be something I can use when working with that individual.

Examine different sociological views on changes in the experience of childhood

There have been many changes in society that have affected children over the last 50 years, however there are several different sociological views on whether these changes have been beneficial to children or not. Functionalist sociologists have the ‘march of progress’ view, as they believe that the experience of childhood has massively improved over the last 50 years. They believe that society is more child-centred today than ever before.The introduction of contraception has led to couples having smaller families, therefore meaning that children now tend to receive more attention from their parents. Similarly, parents are also able to care for their children better due to the introduction of the welfare state and child benefits. Climbie’s case and ‘Every Child Matters’ has led to the improvement of social services and child protection, meaning childhood is much safer now than it was 50 years ago.Children are also in better health due to the NHS, meani ng more children survive childhood now than ever before. All children can now receive state education up until the age of 18, meaning they are better educated and can achieve much higher in adulthood, whilst experiencing a longer period of youth. All of these changes have improved the experience of childhood and cause Functionalists to believe that things are getting better. However, Marxist and Feminist sociologists disagree, claiming that the march of progress view is too positive.They believe that a child’s experience of childhood depends on their class, ethnicity and gender, and that Functionalists overlook the inequalities between these factors. This is called the ‘conflict’ view. Class has an effect on childhood as generally if a family is poor, the children are more likely to have a poor upbringing. Ethnicity is found to have an effect as Asian parents have been found to be much stricter on their kids.

PROPOSAL ON CLOUD STORAGE SERVICE Research Example | Topics and Well Written Essays - 3250 words

ON CLOUD STORAGE SERVICE - Research Proposal Example Moreover, the proposal further includes indication of the main idea of the Cloud Storage Service that will allow the individuals, professionals, and organizations to understand different technicalities and processes associated with the proposed service. Lastly, the research proposal includes identification and discussion of anticipated benefits for organizations along with brief conclusion of the proposal. It is anticipation of the researcher that the proposed idea will be very beneficial for organizations and will facilitate them in improving and enhancing their different processes and procedures by managing huge volumes of data effectively. INTRODUCTION Due to economics of scale, cloud storage is services that are inexpensive and more consistent than services directly controlled by the ‘end user’. Nonetheless, they as well raise several security and confidentiality issues, as big suppliers become entrusted with mass of potentially ‘sensitive’ records.... ier's resources to execute custom applications; and SaaS (Software as a Service), where clients utilize software that functions on the suppliers infrastructure† (Sandrs, p. 10). Cloud storage services generally come under classification as either private or public. Within a private cloud, the infrastructure is controlled and held by the client and positioned on-premise - to be precise, within the clients region of control. Especially, this indicates that access to customer records is within its control and is simply in the hands of trusted parties. Within a public cloud, the infrastructure is held and supervised by a cloud supplier and is positioned within the supplier's area of control. This indicates that client records are outside its control and un-trusted parties could potentially use it. Storage services founded on public clouds offer clients with scalable, as well as dynamic storage. Because of shifting their records to the cloud, clientele can avoid the expenditure of b uilding and keeping a private storage infrastructure, choosing instead to pay a supplier as a function of its requirements. For the majority of clients, this offers quite a lot of advantages together with accessibility - being capable to access records from everywhere - and trustworthiness - not having to be afraid of backups - at a comparatively lesser cost. Although the advantages of utilizing a public cloud infrastructure are obvious, it initiates considerable safety and confidentiality threats. Actually, it appears that the major obstacle to the implementation of cloud storage is concerned about the privacy and reliability of records. Whereas, until now, clients have been ready to trade privacy for the ease of software services, this is not the case for businesses and governments

Corruption in the Pakistan Government Research Paper

Corruption in the Pakistan Government - Research Paper Example The primary aim of this study is to review the extent of corruption in the Islamic Republic of Pakistan. It will also review whether corruption and poor governance have forced its people to seek other forms of assistance, especially those of illegal militant groups. According to Aristotle â€Å"the deviation or corruption of kingship is tyranny. Both kingship and tyranny are forms of government by a single person, but the tyrant studies his own advantage†¦..the king looks to that of his subjects† (Heidenheimer, 1997, P. 3). The journal article ‘Social sciences and the evolving concept of corruption’ provides more connotations or meaning to the term corruption. In Biblical terms corruption is plainly injustice, while current perception of corruption means accepting of bribes. The French have a broader perspective and sees corruption as all acts of crime done by civil servants and includes the judiciary as well as the people who try to corrupt the above two classes (G ´ENAUX, 2004). But, the definition of the term provided by the OECD, apparently covers all the above perceptions as it defines corruption as â€Å"the abuse of public or private office for personal gain† (OECD, 2008, P. 22). This paper will consider the above definition when reviewing the topic of corruption in Pakistan. Pakistan can definitely be classified as a developing economy and studies have shown that corruption levels are higher here when compared to developed ones. Some developing economies have faster growth rate when compared to others, and there is no perceptible differences in corruption levels in both instances (Rose-Ackerman, 2006, p. 218). It has to be seen whether the above two factors hold good in the case of Pakistan as well. In other words, it has to be seen whether corruption in the country is high or low, and also whether it is comparable with a high growth economy like India, China, or Brazil. The three developing economies mentioned here

The Causes and Impact of the Aryan Migration to India Research Paper

The Causes and Impact of the Aryan Migration to India - Research Paper Example A number of them have gone to Greece and some others to Iran and Afghanistan. From the eastern parts, the Aryans moved to India. The complete process of the Aryan migration has happened between BC 2000 to 1500. â€Å"In the later 20th century, ideas were refined, and migration and acculturation were seen as the methods whereby Indo-Aryans spread into northwest India around 1500 BC. These changes were thought to be in line with changes in thinking about language transfer in general, such as the migration of the Greeks into Greece (between 2100 and 1600 BC), or the Indo-Europeanization of Western Europe (between 2200 and 1300 BC)† (Indo-Aryan Migration para. 2). Aryans are arrived India from the North West side and firstly settled in the territories among the branches of the River Indus. So that there we can see in excess of 1200 such kind of migrant Aryans. One of the highest Civilizations that we can see in the period of 3000 to 1500 BC is the Indus Valley civilizations. Aryan s launched a social caste scheme and that is called as the Varna Vyastha which separated the citizens into 4 groups, that are, Brahmin, Vaishya, Kshatriya and   Shudra.    Causes of Aryan migration to India: There are many causes to migrate Aryains to India. Main causes of Aryan migration to India included the fall in temperature, the stress applied by the yellow-skinned ethnic groups in the north areas and scarcity of food. â€Å"The main thrust of Aryan migration was probably south of the terai region where the tributaries of the river Ganga must have dwindled to the point that they could be easily crossed and where the dry forest could be burned down† (Kulke & Rothermund). The Agni, Aryan fire god was credited with the achievement of colonizing this earth for the Aryans. They closed at the river Gandakk which goes in the plains north of current Gorakhpur and links the Ganga. Unlike the extra tributaries additional to the west, this river looks to have been still comple te of good water for the reason that the Aryans named it sadanira and their blessed texts statement that the land beyond was swampy. Only some audacious pioneers crossed the gandak in due course with no the support of Agni. With the development of royal power in the Aryan kingdoms to the west of the river gandak, escape to the unrestrained east may have been attractive to those Aryans who favored the more democratic tribal organization of previous times to the double tutelage of kings and their Brahmin priests. In the end, Brahmins also crosses the waterway gandak and were greeting there if they did not maintain on subverting the tribal organization by consecrating kings everywhere. â€Å"Aryan culture is a development of the Indus valley culture whose language belongs to the indo European family, possibly spoken in the region as far back as the Neolithic period, in interaction with Dravidian culture† (Flood 31). Impact of Aryan Migration to India:   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Ar yan migration to India created lot of impact to the Indian culture. Many of the scholars made so many arguments regarding the migration of Aryans to India. â€Å"There are several possible arguments against the idea of Aryan invasions. According to the invasion theory, the Aryans were a group of primitive nomads who came out of Central Asia with chariots, iron weapons, and superior battle tactics; and thus overthrew the Indus